Article
Adenylate kinase isozyme 2 is essential for growth and development of Drosophila melanogaster.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 May 2009
Fujisawa Koichi, Murakami Ryutaro, Horiguchi Taigo, Noma Takafumi
Abstract excerpt
Adenylate kinases are phylogenetically widespread, highly conserved, and involved in energy metabolism and energy transfer. Of these, adenylate kinase (AK) isozyme 2 is uniquely localized in the mitochondrial intermembrane space and its physiological role remains largely unknown. In this study, we selected Drosophila melanogaster to analyze its role in vivo. AK isozyme cDNAs were cloned and their gene expressions...
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