Article
Serum alleviates the requirement of the granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced Ras activation for proliferation of BaF3 cells.
FEBS letters - 17 Oct 1994
Sakamaki K, Yonehara S
Abstract excerpt
Deletion analysis of the beta subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor previously defined two cytoplasmic regions required for distinct signaling. The membrane-proximal region is responsible for induction of c-myc and pim-1, and is indispensable for...
Topics
- Animals
- B-Lymphocytes
- Base Sequence
- Blood
- Cell Division
- Cell Line
- Culture Media
- Gene Expression
- Genes, fos
- Granulocyte-Macrophage Colony-Stimulating Factor
- Guanosine Triphosphate
- Interleukin-3
- Mice
- Molecular Sequence Data
- Mutation
- Oligonucleotides, Antisense
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins