Article
Nonlethal sec71-1 and sec72-1 mutations eliminate proteins associated with the Sec63p-BiP complex from S. cerevisiae.
Molecular biology of the cell - 1 Sept 1994
Fang H, Green N
Abstract excerpt
The sec71-1 and sec72-1 mutations were identified by a genetic assay that monitored membrane protein integration into the endoplasmic reticulum (ER) membrane of the yeast Saccharomyces cerevisiae. The mutations inhibited integration of various chimeric membrane proteins and translocation of a sub...
Topics
- Amino Acid Sequence
- Base Sequence
- Fungal Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Macromolecular Substances
- Membrane Proteins
- Membrane Transport Proteins
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins