No mutations in the translated region of exon 1 in the TSH receptor in Graves' thyroid glands.

doi:10.1089/thy.1994.4.151

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Article

No mutations in the translated region of exon 1 in the TSH receptor in Graves' thyroid glands.

Thyroid : official journal of the American Thyroid Association - 1 Jan 1994

Ahmad M F, Stenszky V, Juhazs F, Balázs G, Farid N R

Abstract excerpt

We have amplified a 285 base pair by nested polymerase chain reaction 38 nucleotide downstream from the most 5' transcription initiation site (7) encoding 55 of the 57 residues of exon 1 of the human TSH receptor. These DNA were amplified from 10 tissue blocks of thyroid tissue removed at subtota...

Topics

Base Sequence
Exons
Graves Disease
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Protein Biosynthesis
Receptors, Thyrotropin
Thyroid Gland

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