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Article

Genomic DNA analysis of thyrotropin receptor in a family with hereditary hyperthyroidism.

Endocrine journal - 1 Jun 2000

Aoshima H, Yoshida T, Kobayashi S, Mizushima Y, Kawai S

Abstract excerpt

Mutations of the thyrotropin receptor (TSH-R) gene have been reported in some cases of hyperthyroidism. We report a case of a family that had a high incidence of hyperthyroidism (6/13) which strongly suggested hereditary factors. We then analyzed whether the family had mutations of the TSH-R gene. No significant mutations in exon 10 of the TSH-R gene were found in the patient by restriction fragment length...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Thyrotropin

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Source

Identifiers

PMID: 11036883
DOI: 10.1507/endocrj.47.365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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