[Analysis of the TSH receptor gene structure in Graves' disease by a restriction fragment length polymorphism (RFLP) study].

Article

[Analysis of the TSH receptor gene structure in Graves' disease by a restriction fragment length polymorphism (RFLP) study].

Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1994

Monden T, Yamada M, Mori M

Abstract excerpt

We examined the structure of the TSH receptor gene in thyroid disorders, particularly in Graves' disease by a RFLP study with a cloned human TSH receptor cDNA as a probe. Southern blot analysis indicated that the TSH receptor gene is a single copy gene in the human genome. Although RFLPs were not...

Topics

DNA
DNA Probes
Graves Disease
Humans
Mutation
Polymorphism, Restriction Fragment Length
Receptors, Thyrotropin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.