Analysis of the TSH receptor gene structure in various thyroid disorders: DNA from thyroid adenomas can have large insertions or deletions.

doi:10.1089/thy.1992.2.189

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Article

Analysis of the TSH receptor gene structure in various thyroid disorders: DNA from thyroid adenomas can have large insertions or deletions.

Thyroid : official journal of the American Thyroid Association - 1 Jan 1992

Monden T, Yamada M, Satoh T, Iizuka M, Mori M

Abstract excerpt

We examined the structure of the TSH receptor gene in various thyroid disorders by a restriction fragment length polymorphism (RFLP) study with a cloned human TSH receptor cDNA as a probe. Southern blot analysis of DNAs in peripheral white blood cells obtained from normal individuals revealed a s...

Topics

Blotting, Southern
Genes
Humans
Mutation
Polymorphism, Restriction Fragment Length
Receptors, Thyrotropin
Sequence Deletion
Thyroid Diseases

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