Article
Inherited cancers associated with the RET proto-oncogene.
Current opinion in genetics & development - 1 Jun 1994
Goodfellow P J
Abstract excerpt
Mutations in the RET proto-oncogene have been identified in the constitutional DNA of patients with the inherited disorders multiple endocrine neoplasia type 2A and 2B and familial medullary thyroid carcinoma. This review focuses on the discoveries over the past year that pointed to RET as a cand...
Topics
- Amino Acid Sequence
- Base Sequence
- Carcinoma, Medullary
- Chromosome Mapping
- DNA, Neoplasm
- Genotype
- Humans
- Molecular Sequence Data
- Multiple Endocrine Neoplasia Type 2a
- Multiple Endocrine Neoplasia Type 2b
- Mutation
- Neoplasms
