Frequency, specificity, and phenotype of clonally growing human alloreactive interleukin-2-secreting helper T lymphocyte precursors.

doi:10.1097/00007890-199011000-00021

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Article

Frequency, specificity, and phenotype of clonally growing human alloreactive interleukin-2-secreting helper T lymphocyte precursors.

Transplantation - 1 Nov 1990

Theobald M, Hoffmann T, Bunjes D, Heit W

Abstract excerpt

Limiting dilution cultures were performed to detect allospecific IL-2-secreting helper T lymphocyte precursors (HTL-p) among human peripheral blood mononuclear cells, E-rosette-purified (E+) and cell-sorter-separated CD4+/8- as well as CD4-/8+ T cell subsets. Split-well cultures were set up prior...

Topics

Alleles
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD4 Antigens
CD8 Antigens
Clone Cells
HLA Antigens
Humans
In Vitro Techniques
Interleukin-2
Isoantigens
Leukocytes, Mononuclear
Rosette Formation
T-Lymphocyte Subsets
T-Lymphocytes
T-Lymphocytes, Helper-Inducer

Source

Open in PubMed

Identifiers

PMID: 2146786
DOI: 10.1097/00007890-199011000-00021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2146786-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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