Article
Phenotypic analysis of nylon-wool-adherent suppressor cells that inhibit the effector process of tumour cell lysis by lymphokine-activated killer cells in patients with advanced gastric carcinoma.
Journal of cancer research and clinical oncology - 1 Jan 1994
Koyama S, Fukao K
Abstract excerpt
The causes of down-regulation of cytotoxic immune responses in cancer patients have not been fully evaluated. We previously demonstrated that T-cell-growth-factor-activated peripheral blood lymphocytes (PBL) with the surface phenotype CD8+ CD11b-, from patients with widespread metastasis of gastric carcinoma, inhibited the effector process of lymphokine-activated-killer(LAK)-cell-mediated cytolysis. In this...
Topics
- Adult
- Aged
- Animals
- Antibodies, Monoclonal
- Antigens, CD
- CD11 Antigens
- CD8 Antigens
- Cell Adhesion
- Cell Fractionation
- Female
- Fluorescent Dyes
