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Article

P53 gene mutations in women with breast cancer and a previous history of benign breast disease.

European journal of cancer (Oxford, England : 1990) - 1 Jan 1994

Seth A, Palli D, Mariano J M, Metcalf R, Venanzoni M C, Bianchi S, Kottaridis S D, Papas T S

Abstract excerpt

Mutations of the p53 tumour suppressor gene are the most common genetic lesions in human cancers and have been reported in breast cancer as part of the Li-Fraumeni syndrome. In the present study, we determined frequencies and types of the p53 mutations in breast cancer tissues in women with a history of benign breast disease (BBD) identified in Florence, Italy, with (n = 6) or without (n = 10) a family history of...

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Identifiers

PMID: 7917542
DOI: 10.1016/0959-8049(94)90297-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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