Article
CD4+ and CD8+ T cell expansions using selected TCR V and J gene segments at the onset of giant cell arteritis
1 Dec 1994
Abstract excerpt
OBJECTIVE: To investigate T cell receptor (TCR) V alpha/V beta (and in selected cases, J beta) usage in CD4+ and CD8+ peripheral blood lymphocytes of patients with giant cell arteritis (GCA), before and after treatment, as well as to analyze the HLA types of these patients. METHODS: Flow cytometry, with 10 anti-TCR V-specific monoclonal antibodies (MAb), was used. To analyze J beta usage by cell populations...
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