Article
The distribution of gene segments in T-cell receptor gamma gene rearrangements demonstrates the need for multiple primer sets.
The Journal of molecular diagnostics : JMD - 1 May 2003
Lawnicki Lyle C, Rubocki Ronald J, Chan Wing C, Lytle Deborah M, Greiner Timothy C
Abstract excerpt
Limited data exist regarding the distribution of gene segments used in T-cell receptor gamma gene rearrangements (TCR gamma GR) in T-cell lymphoproliferative disorders. The reported efficacy of TCR gamma GR protocols ranges from 60% to greater than 90%. Laboratories reporting a lower detection rate tend to use a limited set of primers. The goal of our study was to provide TCR gamma GR data to demonstrate the...
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