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Article

Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria.

The Journal of cell biology - 1 Jul 1994

Höhfeld J, Hartl F U

Abstract excerpt

Protein folding in mitochondria is mediated by the chaperonin Hsp60, the homologue of E. coli GroEL. Mitochondria also contain a homologue of the cochaperonin GroES, called Hsp10, which is a functional regulator of the chaperonin. To define the in vivo role of the co-chaperonin, we have used the genetic and biochemical potential of the yeast S. cerevisiae. The HSP10 gene was cloned and sequenced and...

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Identifiers

PMID: 7913473
DOI: 10.1083/jcb.126.2.305
PMCID: PMC2200036

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DHFR

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