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Article

Structural and functional requirements for activity of the Tim9-Tim10 complex in mitochondrial protein import.

Molecular biology of the cell - 1 Feb 2009

Baker Michael J, Webb Chaille T, Stroud David A, Palmer Catherine S, Frazier Ann E, Guiard Bernard, Chacinska Agnieszka, Gulbis Jacqueline M, Ryan Michael T

Abstract excerpt

The Tim9-Tim10 complex plays an essential role in mitochondrial protein import by chaperoning select hydrophobic precursor proteins across the intermembrane space. How the complex interacts with precursors is not clear, although it has been proposed that Tim10 acts in substrate recognition, whereas Tim9 acts in complex stabilization. In this study, we report the structure of the yeast Tim9-Tim10 hexameric...

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Identifiers

PMID: 19037098
DOI: 10.1091/mbc.e08-09-0903
PMCID: PMC2633397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural and functional requirements for activity of the Tim9-Tim10 complex in mitochondrial protein import.PMID 19037098Read ↗

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