Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.

doi:10.1093/carcin/15.7.1365

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Article

Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.

Carcinogenesis - 1 Jul 1994

Oda Y, Tanaka M, Nakanishi I

Abstract excerpt

We examined the point mutations of codons 12, 13 and 61 in K-ras gene by slot blot hybridization analysis following polymerase chain reaction and genotypes of polymorphic N-acetyltransferase (NAT) by Southern blot analysis in 36 colorectal carcinoma tissues obtained at surgery. NAT genotypes of 3...

Topics

Adult
Aged
Arylamine N-Acetyltransferase
Colorectal Neoplasms
Female
Genes, ras
Genotype
Humans
Male
Middle Aged
Point Mutation
Polymorphism, Restriction Fragment Length

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