Article
Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.
Carcinogenesis - 1 Jul 1994
Oda Y, Tanaka M, Nakanishi I
Abstract excerpt
We examined the point mutations of codons 12, 13 and 61 in K-ras gene by slot blot hybridization analysis following polymerase chain reaction and genotypes of polymorphic N-acetyltransferase (NAT) by Southern blot analysis in 36 colorectal carcinoma tissues obtained at surgery. NAT genotypes of 36 autopsied livers from patients without colorectal carcinoma were also determined to compare the populations of each...
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