Article
Molecular genotyping for N-acetylation polymorphism in Japanese patients with colorectal cancer.
Cancer - 15 Dec 1994
Shibuta K, Nakashima T, Abe M, Mashimo M, Mori M, Ueo H, Akiyoshi T, Sugimachi K, Suzuki T
Abstract excerpt
BACKGROUND: N-acetylation polymorphism has been documented as a representative pharmacogenetic trait, and also has been implicated ecogenetically in an individual's susceptibility to cancer. However, there still remains controversy concerning the association between colorectal cancer and N-acetylation polymorphism. METHODS: A newly established molecular genotyping method using polymerase chain reaction-based...
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