Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population.

Pharmacogenetics - 1 Dec 1998

Lee E J, Zhao B, Seow-Choen F

Abstract excerpt

Human hepatic N-acetyltransferase (NAT2) is subject to a genetic polymorphism. Because NAT2 is an important enzyme for the detoxification and/or bioactivation of several carcinogenic arylamines, it has been postulated that the polymorphism of NAT2 gene is associated with the occurrence of colorectal and bladder carcinomas. Several mutations have been described in the human NAT2 gene that have been associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 9918135
DOI: 10.1097/00008571-199812000-00008

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population.PMID 9918135Read ↗

Genetic polymorphisms of N-acetyltransferase 2 and colorectal cancer risk.Semantic proximity Read ↗

A meta-analysis of the relationship between NAT2 polymorphism and colorectal cancer susceptibility.Semantic proximity Read ↗

N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients.Semantic proximity Read ↗

N-acetyltransferase 2 gene polymorphisms are associated with susceptibility to cancer: a meta-analysis.Semantic proximity Read ↗

N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.Semantic proximity Read ↗

Joint effect of polymorphism in the N-acetyltransferase 2 gene and smoking on hepatocellular carcinoma.Semantic proximity Read ↗

Absence of association between N-acetyltransferase 2 acetylator status and colorectal cancer susceptibility: based on evidence from 40 studies.Semantic proximity Read ↗

Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer.Semantic proximity Read ↗

N-acetyltransferase 2 gene polymorphism in patients with colorectal carcinoma.Semantic proximity Read ↗

N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.