Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population.

doi:10.1097/00008571-199812000-00008

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Article

Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population.

Pharmacogenetics - 1 Dec 1998

Lee E J, Zhao B, Seow-Choen F

Abstract excerpt

Human hepatic N-acetyltransferase (NAT2) is subject to a genetic polymorphism. Because NAT2 is an important enzyme for the detoxification and/or bioactivation of several carcinogenic arylamines, it has been postulated that the polymorphism of NAT2 gene is associated with the occurrence of colorec...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Arylamine N-Acetyltransferase
China
Colorectal Neoplasms
Female
Genetic Predisposition to Disease
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic

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