Article
ADH and ALDH genotype profiles in Caucasians with alcohol-related problems and controls.
Addiction (Abingdon, England) - 1 Mar 1993
Gilder F J, Hodgkinson S, Murray R M
Abstract excerpt
Eighty-two Caucasian patients receiving treatment for alcohol-related problems and eighty four controls were DNA typed for variants in the alcohol dehydrogenase (ADH2 and ADH3) and mitochondrial aldehyde dehydrogenase (ALDH2) gene loci. No association was observed between individual, or combined...
Topics
- Adult
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Female
- Gene Frequency
- Genotype
- Humans
- Isoenzymes
- Male
- Middle Aged
- Polymerase Chain Reaction
- Risk Factors
- United Kingdom
