An association study between the Cys311 variant of dopamine D2 receptor gene and schizophrenia in the Okinawan population.

doi:10.1111/j.1440-1819.1997.tb02603.x

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Article

An association study between the Cys311 variant of dopamine D2 receptor gene and schizophrenia in the Okinawan population.

Psychiatry and clinical neurosciences - 1 Dec 1997

Kaneshima M, Higa T, Nakamoto H, Nagamine M

Abstract excerpt

Neuroleptic drugs have a high affinity for the dopamine D2 receptor (DRD2); therefore DRD2 is thought to be a candidate gene for schizophrenia. Arinami et al. have reported a positive association between schizophrenia and the Cys311 variant of the DRD2 gene. We determined the allele frequency of...

Topics

Adolescent
Adult
Aged
Alleles
DNA
Female
Genome
Genotype
Humans
Japan
Male
Middle Aged
Polymorphism, Genetic
Psychiatric Status Rating Scales
Receptors, Dopamine D2
Schizophrenia

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