Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer Incidence in BRCA1 mutation carriers.

Journal of the National Cancer Institute - 18 Sept 2002

Thompson Deborah, Easton Douglas F

Abstract excerpt

BACKGROUND: Germline BRCA1 mutations confer a substantial lifetime risk of breast and ovarian cancer, but whether cancer at other sites is increased is less clear. To evaluate the risks of other cancers in BRCA1 mutation carriers, we conducted a cohort study of 11 847 individuals from 699 families segregating a BRCA1 mutation that were ascertained in 30 centers across Europe and North America. METHODS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Sex Characteristics
Share to Age Factors
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Genes, BRCA1

Share to Genetic Carrier Screening

Share to Neoplasms

Source

Identifiers

PMID: 12237281
DOI: 10.1093/jnci/94.18.1358

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer Incidence in BRCA1 mutation carriers.PMID 12237281Read ↗

Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.Semantic proximity Read ↗

Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program.Semantic proximity Read ↗

Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mutation Carriers.Semantic proximity Read ↗

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants.Semantic proximity Read ↗

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants.Semantic proximity Read ↗

Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study.Semantic proximity Read ↗

BRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarian.Semantic proximity Read ↗

Cancer risks in BRCA2 mutation carriers.Semantic proximity Read ↗

Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations.Semantic proximity Read ↗

Cancer risks in first degree relatives of BRCA1 mutation carriers: effects of mutation and proband disease status.Semantic proximity Read ↗

Occurrence of malignancies other than breast and ovarian cancer in female carriers of a BRCA1/2 germline pathogenic variantSemantic proximity Read ↗

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.