Article
Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program.
Journal of the National Cancer Institute - 18 Sept 2002
Brose Marcia S, Rebbeck Timothy R, Calzone Kathleen A, Stopfer Jill E, Nathanson Katherine L, Weber Barbara L
Abstract excerpt
BACKGROUND: Increasing numbers of BRCA1 mutation carriers are being identified in cancer risk evaluation programs. However, no estimates of cancer risk specific to a clinic-based population of mutation carriers are available. These data are clinically relevant, because estimates based on families ascertained for linkage studies may overestimate cancer risk in mutation carriers, and population-based series may...
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