Article
The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice.
Transplantation - 1 Jan 1994
Vallera D A, Taylor P A, Sprent J, Blazar B R
Abstract excerpt
An expanded pool of unrelated donors (URD) is now being utilized for clinical allogeneic bone marrow transplantation. Because URD transplants can involve a mismatch at least at one genotypic MHC locus, we developed a C57BL/6 congenic mouse model to better understand graft rejection based exclusiv...
Topics
- Alleles
- Animals
- Antibodies, Monoclonal
- Bone Marrow
- Bone Marrow Transplantation
- CD4-Positive T-Lymphocytes
- Flow Cytometry
- Graft Rejection
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Killer Cells, Natural
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- T-Lymphocyte Subsets
- T-Lymphocytes, Regulatory