Article
CD6+ T cell depleted allogeneic bone marrow transplantation from genotypically HLA nonidentical related donors.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Apr 1997
Soiffer R J, Mauch P, Fairclough D, Alyea E, Anderson K, Fisher D, Freedman A, Bartlett-Pandite L, Robertson M, Schlossman R, Gollob J, Marcus K, Murray C, Kuhlman C, Freeman A, Nadler L, Ritz J
Abstract excerpt
The widespread use of allogeneic bone marrow transplantation (BMT) is limited by the availability of suitable donors. Recent attempts to expand the donor pool by employing HLA matched unrelated marrow have been partially successful. However, severe graft-versus-host disease (GVHD) and graft failure remain obstacles and contribute to the substantial morbidity and mortality associated with matched unrelated BMT....
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