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Article

Variable hematopoietic graft rejection and graft-versus-host disease in MHC-matched strains of mice.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 2003

Cao Thai M, Lo Betty, Ranheim Erik A, Grumet F Carl, Shizuru Judith A

Abstract excerpt

MHC typing for human hematopoietic cell transplantation (HCT) from unrelated donors is currently performed by using a combination of serologic and molecular techniques. It has been determined that allelic differences in human MHC molecules, revealed by nucleotide sequencing but not by serologic typing, substantially influence graft rejection and graft-versus-host disease, two serious complications of clinical...

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Identifiers

PMID: 14504392
DOI: 10.1073/pnas.2035077100
PMCID: PMC208799

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