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Article

CD45 congenic bone marrow transplantation: evidence for T cell-mediated immunity.

Stem cells (Dayton, Ohio) - 1 Jan 2004

Xu Hong, Exner Beate G, Chilton Paula M, Schanie Carrie, Ildstad Suzanne T

Abstract excerpt

CD45 congenic mice have been used to study stem cell engraftment in the absence of alloreactivity. Recently, impaired engraftment was reported in this model and attributed to weak immune reactivity. We have confirmed that there is indeed low-level reactivity mediated by CD8(+) cells and alpha beta-TCR(+) T cells. B6 (CD45.2) recipients were conditioned with total body irradiation (TBI) and transplanted with...

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Identifiers

PMID: 15536194
DOI: 10.1634/stemcells.22-6-1039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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