Article
[The expression of mutant p53 (mp53) protein in rat hepatic preneoplastic lesions induced by diethylnitrosamine (DEN)].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jan 1997
Zhu H, Zhang X, Chen Y
Abstract excerpt
OBJECTIVE: To study p53 genes related to hepatocarcinogenesis. METHODS: Using immunohistochemistry techniques, the relation between expression of mp53 protein, placental glutathione S-transferase (GST-P) and the cell proliferative activity was investigated in rat hepatic preneoplastic lesions induced by DEN and the control liver. RESULTS: Two of five rats with hepatic prenoplastic lesions had mp53 protein...
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