[Cell kinetics of colorectal tumors with assessment by K-ras mutation and PCNA labeling index].

Article

[Cell kinetics of colorectal tumors with assessment by K-ras mutation and PCNA labeling index].

Nihon Geka Gakkai zasshi - 1 Dec 1993

Tanaka M, Omura K, Ishida F, Watanabe Y

Abstract excerpt

K-ras mutations in colorectal tumors (53 carcinomas, 21 adenomas) were investigated using oligonucleotide probes specific for mutations at codon 12, 13, or 61 of the K-ras gene by polymerase chain reaction and oligonucleotide hybridization techniques, and the proliferative activities were assesse...

Topics

Adenoma
Aged
Carcinoma
Cell Cycle
Colorectal Neoplasms
Female
Genes, ras
Humans
Male
Middle Aged
Mutation
Nuclear Proteins
Oligonucleotide Probes
Polymerase Chain Reaction
Proliferating Cell Nuclear Antigen

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