Article
[Cell kinetics of colorectal tumors with assessment by K-ras mutation and PCNA labeling index].
Nihon Geka Gakkai zasshi - 1 Dec 1993
Tanaka M, Omura K, Ishida F, Watanabe Y
Abstract excerpt
K-ras mutations in colorectal tumors (53 carcinomas, 21 adenomas) were investigated using oligonucleotide probes specific for mutations at codon 12, 13, or 61 of the K-ras gene by polymerase chain reaction and oligonucleotide hybridization techniques, and the proliferative activities were assessed immunohistochemically by using anti-proliferating cell nuclear antigen (PCNA), counting PCNA labeling index (LI)....
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