Association of a variable number of tandem repeats (VNTR) in glycoprotein Ib alpha and HPA-2 alloantigens.

Article

Association of a variable number of tandem repeats (VNTR) in glycoprotein Ib alpha and HPA-2 alloantigens.

Thrombosis and haemostasis - 1 Nov 1994

Simsek S, Bleeker P M, van der Schoot C E, von dem Borne A E

Abstract excerpt

The human platelet alloantigen HPA-2(Koa/Kob) system is involved in two clinical syndromes, neonatal alloimmune thrombocytopenia and platelet transfusion refractoriness. We have previously described that the human platelet alloantigens HPA-2a(Kob) and HPA-2b(Koa), are caused by a Thr145Met amino...

Topics

Alleles
Base Sequence
Europe
Genotype
Humans
Isoantigens
Pedigree
Platelet Membrane Glycoproteins
Polymorphism, Genetic
Repetitive Sequences, Nucleic Acid
White People

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