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Single point mutation in human glycoprotein IIIa is associated with a new platelet-specific alloantigen (Mo) involved in neonatal alloimmune thrombocytopenia

1993-01-01

Abstract excerpt

Here we describe a new platelet-specific alloantigen that was identified in a case of neonatal alloimmune thrombocytopenia. This antigen has provisionally been called “Mo.” By studying the Mo family, it was shown to be inherited in an autosomal dominant manner. Immunoprecipitation and Western blot analysis showed that the antigen resides on platelet glycoprotein IIIa (GP IIIa). Genomic analysis, performed by apply...

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Literature Corpus work
37f7962e-d8b5-5171-8b5f-5375126c2fb1
DOI
10.1182/blood.v81.1.70.bloodjournal81170
Open publication

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Single point mutation in human glycoprotein IIIa is associated with a new platelet-specific alloantigen (Mo) involved in neonatal alloimmune thrombocytopeniaDOI 10.1182/blood.v81.1.70.bloodjournal81170
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