Article
Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations.
RNA (New York, N.Y.) - 16 Jul 2024
Babina Arianne M, Kirsebom Leif A, Andersson Dan I
Abstract excerpt
RNase P is an essential enzyme found across all domains of life that is responsible for the 5'-end maturation of precursor tRNAs. For decades, numerous studies have sought to elucidate the mechanisms and biochemistry governing RNase P function. However, much remains unknown about the regulation of RNase P expression, the turnover and degradation of the enzyme, and the mechanisms underlying the phenotypes and...
Topics
- Escherichia coli
- Escherichia coli Proteins
- Ribonuclease P
- Phenotype
- Mutation
- Protease La
- Suppression, Genetic
- Temperature