Article
Quantification of the mononuclear phagocyte response to Wallerian degeneration of the optic nerve.
Journal of neurocytology - 1 Dec 1994
Lawson L J, Frost L, Risbridger J, Fearn S, Perry V H
Abstract excerpt
We investigated the numbers, origin and phenotype of mononuclear phagocytes (macrophages/microglia) responding to Wallerian degeneration of the mouse optic nerve in order to compare it with the response to Wallerian degeneration in the PNS, already described. We found macrophage/microglial numbers elevated nearly four fold in the distal segments of crushed optic nerves and their projection areas in the...
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