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Article

Lysophosphatidic acid and bradykinin have opposite effects on phenotypic transformation of normal rat kidney cells.

Journal of cellular biochemistry - 1 Dec 1994

Afink G B, Van Alewijk D C, De Roos A D, Van Zoelen E J

Abstract excerpt

The bioactive lipid lysophosphatidic acid is besides a strong mitogen for quiescent fibroblasts, a potent inducer of phenotypic transformation of normal rat kidney cells. The lysophosphatidic acid induced loss of density-arrest is strongly inhibited by bradykinin. Although their effects on normal rat kidney cell proliferation are opposite, bradykinin mimics many of the intracellular effects induced upon...

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PMID: 7890806
DOI: 10.1002/jcb.240560408

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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