Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.

doi:10.1136/gut.36.1.81

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Article

Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.

Gut - 1 Jan 1995

Smith-Ravin J, England J, Talbot I C, Bodmer W

Abstract excerpt

Colonic exfoliated epithelial cells in faecal material provide a source of human DNA which has been analysed for the presence of the tumour marker ras, in order to detect early tumour cells. The stool samples were subjected to a preliminary sample preparation step followed by centrifugation. DNA...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Colonic Neoplasms
DNA, Neoplasm
Feces
Female
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Rectal Neoplasms

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