Article
Detection of c-Ki-ras mutations in faecal samples from sporadic colorectal cancer patients.
Gut - 1 Jan 1995
Smith-Ravin J, England J, Talbot I C, Bodmer W
Abstract excerpt
Colonic exfoliated epithelial cells in faecal material provide a source of human DNA which has been analysed for the presence of the tumour marker ras, in order to detect early tumour cells. The stool samples were subjected to a preliminary sample preparation step followed by centrifugation. DNA was extracted from both the centrifugation pellet and supernatant fractions, as well as from endoscopy washings, using...
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