Article
Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.
Journal of neurosurgery - 1 Sept 1994
Lang F F, Miller D C, Koslow M, Newcomb E W
Abstract excerpt
To characterize some of the genetic events underlying the development of glioblastoma multiforme, the authors analyzed 65 astrocytic tumors (seven pilocytic astrocytomas, eight astrocytomas, 16 anaplastic astrocytomas, and 34 glioblastomas multiforme) for loss of heterozygosity for chromosome 17p...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Astrocytoma
- Brain Neoplasms
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 17
- DNA, Neoplasm
- ErbB Receptors
- Female
- Gene Amplification
- Genes, myc
- Genes, p53
- Genes, ras