Article
Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging.
Annals of the New York Academy of Sciences - 16 Dec 1996
Small G W, Komo S, La Rue A, Saxena S, Phelps M E, Mazziotta J C, Saunders A M, Haines J L, Pericak-Vance M A, Roses A D
Abstract excerpt
New treatments for Alzheimer's disease (AD) are more likely to slow or halt disease progression rather than to reverse existing neuronal damage. Identifying persons with mild cognitive complaints who are at risk for AD will allow investigators to apply anti-dementia treatments before extensive brain damage develops. The discovery of the apolipoprotein E epsilon 4 allele (APOE epsilon 4) as a major risk factor for...
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