Genetic and phenotypic markers and their relationship to product quality and consistency.

Article

Genetic and phenotypic markers and their relationship to product quality and consistency.

Developments in biological standardization - 1 Jan 1994

Adamson S R, Charlebois T S

Abstract excerpt

Manufacturers of products derived from biological systems have long sought to identify relevant genotypic and phenotypic markers displayed by production strains and cell lines which could be employed as in-process monitors to predict product quality. Ideally, changes in these markers would signal...

Topics

Animals
Biotechnology
CHO Cells
Cell Division
Cloning, Molecular
Cricetinae
Culture Media
Cytological Techniques
DNA, Recombinant
Genetic Markers
Phenotype
Quality Control
Recombinant Proteins
Sequence Analysis, DNA

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