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Article

Peptide mapping for detecting variants in protein products.

Developments in biological standardization - 1 Jan 1992

Garnick R L

Abstract excerpt

The genetic stability of biotechnology production systems is of importance in evaluating the safety and efficacy of protein products. The analysis methods currently available for assessing the genetic stability of such systems are limited by the complexity of the eukaryotic genome and by their inability to predict the effects of post-transcriptional and post-translational events, such as glycosylation or host...

Topics

Amino Acid Sequence
Animals
Biological Products
Deoxyribonucleases
Genetic Variation
Molecular Sequence Data
Mutagenesis, Site-Directed
Peptide Fragments
Peptide Mapping
Recombinant Proteins
Safety

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Identifiers

PMID: 1478332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1478332-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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