Article
Qualitatively distinct phenotypes in the design space of biochemical systems.
FEBS letters - 17 Dec 2009
Savageau Michael A, Fasani Rick A
Abstract excerpt
Although characterization of the genotype has undergone revolutionary advances as a result of the successful genome projects, the chasm between our understanding of a fully characterized gene sequence and the phenotypic repertoire of the organism is as broad and deep as it was in the pre-genomic era. There are two fundamental unsolved problems that provide the context for the challenges in relating genotype to...
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