Article
[Mutations of glucokinase gene in Japanese subjects with NIDDM].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Hinata S, Nishi S, Matsukage T, Yoshimi T
Abstract excerpt
Glucokinase has been proposed to play an important role as a glucose sensor in pancreatic beta-cells. Mutations in the glucokinase gene have been shown to be the major cause of maturity-onset diabetes of the young (MODY) in Caucasian subjects. In population-association study with microsatellite D...
Topics
- Asian People
- Diabetes Mellitus, Type 2
- Glucokinase
- Humans
- Japan
- Mutation
- Polymerase Chain Reaction
