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Article

Clinical characteristics of Japanese men with glucokinase gene beta-cell promoter variant.

Diabetes care - 1 Jul 1997

Yamada K, Yuan X, Ishiyama S, Ichikawa F, Koyama K I, Koyanagi A, Koyama W, Nonaka K

Abstract excerpt

OBJECTIVE: To study the association between a variant at the position of -30 of beta-cell-specific promoter of the glucokinase gene and glucose tolerance in the Japanese general population and to assess the clinical characteristics of subjects with the variant. RESEARCH DESIGN AND METHODS: The genotype of 657 Japanese men aged 51.0 +/- 8.8 years (mean +/- SD) was analyzed by an allele-specific assay using...

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PMID: 9203455
DOI: 10.2337/diacare.20.7.1159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical characteristics of Japanese men with glucokinase gene beta-cell promoter variant.PMID 9203455Read ↗

A variation at position -30 of the beta-cell glucokinase gene promoter is associated with reduced beta-cell function in middle-aged Japanese-American men.Semantic proximity Read ↗

The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians.Semantic proximity Read ↗

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Glucokinase gene variations in Japanese-Americans with a family history of NIDDM.Semantic proximity Read ↗

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.Semantic proximity Read ↗

The beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus. Diabetes Incidence Study in Sweden (DISS).Semantic proximity Read ↗

Sequence variations of the glucokinase gene in Japanese subjects with NIDDM.Semantic proximity Read ↗

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