Article
Glucokinase gene variants in the common form of NIDDM.
Diabetes - 1 Apr 1993
Chiu K C, Tanizawa Y, Permutt M A
Abstract excerpt
To determine whether a structural defect in glucokinase could be a primary cause of glucose intolerance in the common form of NIDDM, the prevalence of mutations in the gene in 60 American black NIDDM patients was investigated. First, by Southern blot analysis of DNA from a subset of randomly selected subjects (n = 20), no gross deletions, insertions, or rearrangements of the gene were detected. Next, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.