Article
[Parathyroid cells: structure of Ca2+ sensing receptor].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1995
Yoshimoto K, Saito S
Abstract excerpt
Using expression in Xenopus oocytes, Brown et al. cloned a bovine parathyroid Ca2+ sensing receptor (BoPCaR1). The 1,085 amino acid membrane protein is included in a class of putative seven transmembrane-spanning structures that activate the phosphoinositol pathway through G proteins. Receptor activation presumably elevates intracellular Ca2+ to inhibit secretion of PTH. BoPCaR1 has a big extracellular domain at...
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