Article
A study of the association of HLA DR, DQ, and complement C4 alleles with systemic lupus erythematosus in Iceland.
Annals of the rheumatic diseases - 1 Aug 1998
Steinsson K, Jónsdóttir S, Arason G J, Kristjánsdóttir H, Fossdal R, Skaftadóttir I, Arnason A
Abstract excerpt
OBJECTIVE: To perform an exploratory analysis of the relative contribution of single MHC genes to the pathogenesis of systemic lupus erythematosus (SLE) in a homogenous white population. METHODS: MHC class II alleles and C4 allotypes were determined in 64 SLE patients and in ethnically matched co...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Child
- Complement C4
- Female
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Iceland
- Lupus Erythematosus, Systemic
- Male
- Middle Aged