Article
A study of the association of HLA DR, DQ, and complement C4 alleles with systemic lupus erythematosus in Iceland.
Annals of the rheumatic diseases - 1 Aug 1998
Steinsson K, Jónsdóttir S, Arason G J, Kristjánsdóttir H, Fossdal R, Skaftadóttir I, Arnason A
Abstract excerpt
OBJECTIVE: To perform an exploratory analysis of the relative contribution of single MHC genes to the pathogenesis of systemic lupus erythematosus (SLE) in a homogenous white population. METHODS: MHC class II alleles and C4 allotypes were determined in 64 SLE patients and in ethnically matched controls. HLA-DR and DQ typing was performed by polymerase chain reaction amplification with sequence specific primers....
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