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Article

kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire.

The Journal of experimental medicine - 1 Mar 1995

Giachino C, Padovan E, Lanzavecchia A

Abstract excerpt

It is a common notion that mature B lymphocytes express either kappa or lambda light (L) chains, although the mechanism that leads to such isotypic exclusion is still debated. We have investigated the extent of L chain isotypic exclusion in normal human peripheral blood B lymphocytes. By three-color staining with anti-CD19, anti-kappa, and anti-lambda antibodies we could estimate that 0.2-0.5% of peripheral blood...

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Source

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Identifiers

PMID: 7869042
DOI: 10.1084/jem.181.3.1245
PMCID: PMC2191910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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