Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant.

Molecular biology of the cell - 1 Nov 1994

Kadowaki T, Hitomi M, Chen S, Tartakoff A M

Abstract excerpt

We have identified a set of genes that affect mRNA transport (mtr) from the nucleus to the cytoplasm of Saccharomyces cerevisiae. One of these genes, MTR2, has been cloned and shown to encode a novel 21-kDa nuclear protein that is essential for vegetative growth. MTR2 shows limited homology to a protein implicated in plasmid DNA transfer in Escherichia coli. PolyA+RNA accumulates within the nucleus of mtr2-1 in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 7865887
DOI: 10.1091/mbc.5.11.1253
PMCID: PMC301150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant.PMID 7865887Read ↗

Cotransport of the heterodimeric small subunit of the Saccharomyces cerevisiae ribonucleotide reductase between the nucleus and the cytoplasm.Semantic proximity Read ↗

Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein.Semantic proximity Read ↗

Genome-wide screen uncovers novel pathways for tRNA processing and nuclear-cytoplasmic dynamics.Semantic proximity Read ↗

Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene.Semantic proximity Read ↗

Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.Semantic proximity Read ↗

A conditional yeast mutant deficient in mRNA transport from nucleus to cytoplasm.Semantic proximity Read ↗

Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants.Semantic proximity Read ↗

The arginine methyltransferase Rmt2 is enriched in the nucleus and co-purifies with the nuclear porins Nup49, Nup57 and Nup100.Semantic proximity Read ↗

The DECD box putative ATPase Sub2p is an early mRNA export factor.Semantic proximity Read ↗

The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress.Semantic proximity Read ↗

Rbs1, a new protein implicated in RNA polymerase III biogenesis in yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.