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Article

Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants.

The Journal of cell biology - 1 Aug 1994

Kadowaki T, Chen S, Hitomi M, Jacobs E, Kumagai C, Liang S, Schneiter R, Singleton D, Wisniewska J, Tartakoff A M

Abstract excerpt

To understand the mechanisms of mRNA transport in eukaryotes, we have isolated Saccharomyces cerevisiae temperature-sensitive (ts) mutants which accumulate poly(A)+ RNA in the nucleus at the restrictive temperature. A total of 21 recessive mutants were isolated and classified into 16 complementation groups. Backcrossed mRNA transport-defective strains from each complementation group have been analyzed. A strain...

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Identifiers

PMID: 8045930
DOI: 10.1083/jcb.126.3.649
PMCID: PMC2120137

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