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Article

Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea.

Journal of hepatology - 1 Jan 2003

Yoo Byung Chul, Park Joong-Won, Kim Hyung Joon, Lee Dong Ho, Cha Young Ju, Park Sill Moo

Abstract excerpt

BACKGROUND/AIMS: The aims of this study were to determine the frequency of precore/core promoter mutations and hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (e-CHB) in Korea. METHODS: Patients with chronic hepatitis B virus (HBV) infection were tested for HBeAg, anti-HBe, liver profile and HBV-DNA by a branched DNA (bDNA) assay. Serum HBV-DNA was amplified by a polymerase chain reaction and the...

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PMID: 12480566
DOI: 10.1016/s0168-8278(02)00349-5

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