Article
MafA has strong cell transforming ability but is a weak transactivator.
Oncogene - 11 Sept 2003
Nishizawa Makoto, Kataoka Kohsuke, Vogt Peter K
Abstract excerpt
The maf oncogene of the avian oncogenic retrovirus AS42 encodes a nuclear bZip protein, v-Maf, that recognizes sequences related to the AP-1 target site. The corresponding cellular protein, c-Maf belongs to a family of related bZip proteins together with MafA and MafB. In this paper, we compare the transactivation and cell transforming abilities of MafA and MafB along with two forms of the c-Maf protein. These...
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