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Article

A comparison of transcriptional activation by ER alpha and ER beta.

The Journal of steroid biochemistry and molecular biology - 1 Jan 2000

Cowley S M, Parker M G

Abstract excerpt

We have compared the ability of ER alpha and ER beta to stimulate transcription from a number of reporter genes in different cell lines and demonstrate that the activity of AF1 in ER beta is negligible compared with that of ER alpha on ERE based reporters. The activity of AF2 in ER alpha and ER beta is similar and this is likely to reflect their similar ability to bind coactivators. As a consequence, when...

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Identifiers

PMID: 10418990
DOI: 10.1016/s0960-0760(99)00055-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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